SCHEMBL13708200

SCHEMBL13708200

COc1ccc(/C=C2/OCN(C(C)=O)C2=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
DYRK1A Q13627 2/20 0.45
DYRK1B Q9Y463 2/20 0.45
MAPT P10636 1/20 0.45
HSD17B3 P37058 2/20 0.44
CLK1 P49759 1/20 0.43
AKR1B1 P15121 2/20 0.43
ACHE P22303 1/20 0.42
MAOB P27338 1/20 0.42
PRKCA P17252 1/20 0.42
PRKCE Q02156 1/20 0.42
RASGRP3 Q8IV61 1/20 0.42
KIT P10721 1/20 0.41
CYP1A2 P05177 1/20 0.41
PARP1 P09874 1/20 0.41
CA9 Q16790 1/20 0.41
PIM1 P11309 1/20 0.40
PIM2 Q9P1W9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85753 0.72 ALDH1A1 (0.69) ALDH1A1LMNASMN1; SMN2MAPTHSD17B3
SCHEMBL8411264 0.71 HRH3 (0.64) ALDH1A1DYRK1ADYRK1BCLK1AKR1B1
SCHEMBL8411774 0.71 PABPC1 (0.54) ALDH1A1LMNASMN1; SMN2MAPTAKR1B1
SCHEMBL14091995 0.71 ALDH1A1 (0.47) ALDH1A1LMNASMN1; SMN2DYRK1ADYRK1B
SCHEMBL8573167 0.71 HRH3 (0.64) ALDH1A1DYRK1ADYRK1BCLK1AKR1B1
SCHEMBL8411263 0.71 HRH3 (0.64) ALDH1A1DYRK1ADYRK1BCLK1AKR1B1
SCHEMBL8411772 0.71 PABPC1 (0.54) ALDH1A1LMNASMN1; SMN2MAPTAKR1B1
SCHEMBL8412001 0.71 PABPC1 (0.54) ALDH1A1LMNASMN1; SMN2MAPTAKR1B1
SCHEMBL8413379 0.70 AKR1B1 (0.51) ALDH1A1LMNASMN1; SMN2MAPTAKR1B1
SCHEMBL8413375 0.70 AKR1B1 (0.51) ALDH1A1LMNASMN1; SMN2MAPTAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105800-A2 Processing solution for preparing lithographic printing plate and processing method of lithographic printing plate precursor FUJIFILM Corporation (JP) 2009-09-30 EP disclosed