Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 3/20 | 0.57 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.57 |
| ▸ | GALK1 | P51570 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | XPA | P23025 | 8/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290357 | 0.87 | ALDH1A1 (0.73) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL8291273 | 0.81 | MEN1 (0.49) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL14581383 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL31358892 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL18920608 | 0.77 | ALDH1A1 (0.83) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL8290675 | 0.76 | ALDH1A1 (0.59) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL8292183 | 0.75 | KMT2A (0.58) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL13708915 | 0.74 | ESR2 (0.62) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL8291360 | 0.73 | ALDH1A1 (0.59) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL8290432 | 0.72 | ESR2 (0.72) | ALDH1A1KMT2AKDM4EPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105441-A1 | Alanyl aminopeptidase and dipeptidylpeptidase IV dual inhibitors for the treatment of immunological, inflammatory, neuronal and other illnesses | IMTM GmbH (DE) | 2009-09-30 | — | — | EP | disclosed |