Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17275642 | 0.85 | ACHE (0.48) | ACHEOPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL3501876 | 0.82 | ACHE (0.48) | ACHEOPRM1OPRK1OPRD1SMN1; SMN2 | |
| SCHEMBL17276366 | 0.79 | ACHE (0.43) | ACHEOPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL17276390 | 0.79 | ACHE (0.46) | ACHEOPRM1OPRK1OPRD1 | |
| SCHEMBL2096904 | 0.77 | DRD1 (0.48) | ACHESMN1; SMN2MAPTCHRM2CHRM4 | |
| SCHEMBL25177736 | 0.75 | BRD4 (0.48) | ACHEALDH1A1TP53SMN1; SMN2MGLL | |
| SCHEMBL3503283 | 0.74 | ALDH1A1 (0.50) | ACHEOPRM1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL30317408 | 0.74 | ROCK1 (0.48) | ACHEALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25184947 | 0.74 | ROCK1 (0.48) | ACHEALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL26149606 | 0.74 | ACHE (0.43) | ACHEOPRM1ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |