Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.48 |
| ▸ | DRD5 | P21918 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | DRD3 | P35462 | 7/20 | 0.48 |
| ▸ | DRD4 | P21917 | 6/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097897 | 0.90 | ESR2 (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL28109941 | 0.90 | CHRM2 (0.48) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL17602223 | 0.87 | DRD1 (0.48) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL3433243 | 0.84 | CHRM2 (0.44) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL25177736 | 0.82 | BRD4 (0.48) | DRD1ACHESIGMAR1SMN1; SMN2MAPT | |
| SCHEMBL26149606 | 0.81 | ACHE (0.43) | ACHESIGMAR1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL3501876 | 0.80 | ACHE (0.48) | DRD2DRD3DRD4CHRM2CHRM4 | |
| SCHEMBL11601096 | 0.80 | SMN1; SMN2 (0.49) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL29478502 | 0.79 | ROCK1 (0.51) | SIGMAR1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL693233 | 0.79 | ROCK1 (0.51) | SIGMAR1SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163910-B2 | Amide-substituted xanthene dyes | ELITECH HOLDING B.V. (NL) | 2012-04-24 | — | — | US | disclosed |
| US-7767834-B2 | Phosphonylated fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2010-08-03 | — | — | US | disclosed |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | US | disclosed |
| WO-2009046165-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| EP-1991552-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | Epoch Biosciences, Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| WO-2007098182-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20060199955-A1 | Phosphonylated fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | DRD1 4050/4885DRD5 2128/4885DRD2 4108/4885 |
| US-20060199955-A1 | Phosphonylated fluorescent dyes and conjugates | PHOSPHO1, PFAS, PHPT1 | DRD1 4050/4885DRD5 2128/4885DRD2 4108/4885 |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | ANXA5, PHOSPHO1, TPST2 | DRD1 4268/4885DRD5 3357/4885DRD2 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.