Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.81 |
| ▸ | CASP6 | P55212 | 20/20 | 0.81 |
| ▸ | CASP8 | Q14790 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14582926 | 0.84 | CASP3 (0.58) | CASP3CASP6CASP8 | |
| SCHEMBL14582953 | 0.82 | ANPEP (0.58) | CASP3CASP6CASP8 | |
| SCHEMBL14582929 | 0.77 | ANPEP (0.57) | CASP3CASP6CASP8 | |
| SCHEMBL14598408 | 0.76 | CASP3 (0.60) | CASP3CASP6CASP8 | |
| SCHEMBL4551966 | 0.75 | CASP3 (0.54) | CASP3CASP6CASP8 | |
| SCHEMBL7204618 | 0.75 | CASP3 (0.59) | CASP3CASP6CASP8 | |
| SCHEMBL14582930 | 0.74 | CASP3 (0.75) | CASP3CASP6CASP8 | |
| SCHEMBL5497139 | 0.73 | CASP3 (0.53) | CASP3CASP6CASP8 | |
| SCHEMBL24939045 | 0.73 | CASP3 (0.47) | CASP3CASP6CASP8 | |
| SCHEMBL30276938 | 0.73 | CTSL (0.47) | CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754475-B1 | Use of C-terminal modified oxamyl dipeptides as inhibitors of the ice/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS INC (US) | 2009-09-16 | — | — | EP | disclosed |
| US-7183260-B2 | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183260-B2 | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS, INC. (US) | 2007-02-27 | — | — | US | disclosed |