Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 18/20 | 0.59 |
| ▸ | CASP6 | P55212 | 17/20 | 0.59 |
| ▸ | CASP8 | Q14790 | 17/20 | 0.59 |
| ▸ | CLPP | Q16740 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14598408 | 0.88 | CASP3 (0.60) | CASP3CASP6CASP8CASP1CASP7 | |
| SCHEMBL5497139 | 0.88 | CASP3 (0.53) | CASP3CASP6CASP8 | |
| SCHEMBL7201964 | 0.83 | CASP3 (0.48) | CASP3CASP6CASP8CLPPCASP1 | |
| SCHEMBL7201963 | 0.83 | CASP3 (0.48) | CASP3CASP6CASP8CLPPCASP1 | |
| SCHEMBL6830895 | 0.82 | CASP3 (0.43) | CASP3CASP6CASP8CLPPCASP1 | |
| SCHEMBL5495594 | 0.75 | CASP3 (0.56) | CASP3CASP6CASP8CASP1CASP7 | |
| SCHEMBL5495598 | 0.75 | CASP3 (0.56) | CASP3CASP6CASP8CASP1CASP7 | |
| SCHEMBL13709296 | 0.75 | CASP3 (0.81) | CASP3CASP6CASP8 | |
| SCHEMBL14598409 | 0.72 | CASP3 (0.58) | CASP3CASP6CASP8CLPPCASP1 | |
| SCHEMBL8353758 | 0.71 | CASP3 (0.46) | CASP3CASP6CASP8CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232788-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS, INC. | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232788-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | DPP3, IAPP, CASP3 | CASP3 3/4885CASP6 26/4885CASP8 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.