Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875923 | 0.88 | DHFR (0.40) | KMT2A | |
| SCHEMBL135692 | 0.87 | KMT2A (0.46) | KMT2A | |
| SCHEMBL15875922 | 0.81 | — | — | |
| SCHEMBL137101 | 0.76 | KMT2A (0.35) | LTB4RKMT2A | |
| SCHEMBL139225 | 0.73 | KMT2A (0.55) | KMT2A | |
| SCHEMBL3475837 | 0.73 | KMT2A (0.50) | KMT2A | |
| SCHEMBL142736 | 0.72 | KMT2A (0.58) | KMT2A | |
| SCHEMBL134952 | 0.71 | KMT2A (0.51) | KMT2A | |
| SCHEMBL140590 | 0.71 | KMT2A (0.50) | KMT2A | |
| SCHEMBL15875940 | 0.71 | KMT2A (0.64) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059028-A1 | THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059028-A1 | THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | TYMP, DUT, MAVS | LTB4R 817/4885KMT2A 2903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.