Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1370124 | 0.95 | XDH (0.35) | XDHMAPTL3MBTL1HDAC8TDP1 | |
| SCHEMBL1370481 | 0.93 | HDAC8 (0.38) | XDHMAPTL3MBTL1HDAC8TDP1 | |
| SCHEMBL1370007 | 0.92 | L3MBTL1 (0.38) | XDHMAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL1369226 | 0.85 | CA1 (0.41) | MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL1369867 | 0.83 | XDH (0.44) | XDHMAPTTP53TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL1371882 | 0.82 | XDH (0.43) | XDHMAPTTP53TSHRHSD17B10 | |
| SCHEMBL1369301 | 0.82 | XDH (0.42) | XDHTP53TSHRHSD17B10KDM4E | |
| SCHEMBL1370043 | 0.81 | CA1 (0.49) | XDHMAPTL3MBTL1TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL1369764 | 0.81 | XDH (0.41) | XDHTP53TSHRHSD17B10KDM4E | |
| SCHEMBL1371416 | 0.80 | XDH (0.41) | XDHTP53TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | claimed |
| EP-2303884-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2011-04-06 | — | — | EP | claimed |
| WO-2010000429-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-07 | — | — | WO | claimed |
| EP-2141166-A1 | Adenine receptor ligands | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-06 | — | — | EP | claimed |
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | disclosed |
| EP-2303884-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010000429-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-07 | — | — | WO | disclosed |
| EP-2141166-A1 | Adenine receptor ligands | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | ADORA2A, ADORA1, ADORA3 | XDH 408/4885MAPT 2289/4885L3MBTL1 2483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.