Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890009 | 0.94 | ALDH1A1 (0.32) | LMNAALDH1A1THRBTP53 | |
| SCHEMBL4481255 | 0.94 | ALDH1A1 (0.32) | LMNAALDH1A1THRBTP53 | |
| SCHEMBL4484765 | 0.94 | NPC1 (0.34) | LMNAALDH1A1THRBMAPTTP53 | |
| SCHEMBL4493109 | 0.91 | MMP2 (0.33) | LMNAALDH1A1THRBRECQLMAPT | |
| SCHEMBL13712219 | 0.89 | HTR2A (0.32) | — | |
| SCHEMBL4488210 | 0.89 | HTR2A (0.32) | — | |
| SCHEMBL4480672 | 0.89 | MMP2 (0.31) | LMNAALDH1A1THRBRECQLTP53 | |
| SCHEMBL13712260 | 0.88 | MMP2 (0.31) | LMNAALDH1A1THRBRECQLMMP2 | |
| SCHEMBL4489808 | 0.88 | MMP2 (0.31) | LMNAALDH1A1THRBRECQLMMP2 | |
| SCHEMBL4495326 | 0.88 | MEN1 (0.33) | LMNAALDH1A1THRBRECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582626-B2 | 5,6-dihydro-1H-pyridin-2-one compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2009-09-01 | — | — | US | disclosed |