Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13712966 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM3TAS1R3TAS1R1 | |
| SCHEMBL17086357 | 0.96 | TAS1R3 (0.46) | CHRM2CHRM4CHRM3TAS1R3TAS1R1 | |
| SCHEMBL13712968 | 0.82 | TAS1R3 (0.46) | TAS1R3TAS1R1PSEN1PSEN2APH1B | |
| SCHEMBL29297310 | 0.82 | CHRM2 (0.44) | CHRM2CHRM4CHRM3TAS1R3TAS1R1 | |
| SCHEMBL14161210 | 0.82 | CHRM2 (0.44) | CHRM2CHRM4CHRM3TAS1R3TAS1R1 | |
| SCHEMBL14161205 | 0.82 | CHRM2 (0.44) | CHRM2CHRM4CHRM3TAS1R3TAS1R1 | |
| SCHEMBL9133791 | 0.80 | CHRM2 (0.53) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL9133786 | 0.80 | CHRM2 (0.53) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL4614064 | 0.80 | CHRM2 (0.53) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL24618694 | 0.78 | CHRM2 (0.42) | CHRM2CHRM4CHRM3TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582626-B2 | 5,6-dihydro-1H-pyridin-2-one compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090111798-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111798-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | HAVCR2, PYGL, HCCS | CHRM2 2998/4885CHRM4 2402/4885CHRM3 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.