Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065171 | 0.89 | KMT2A (0.52) | ALDH1A1KDM4EHTTTDP1KMT2A | |
| SCHEMBL6189800 | 0.78 | NR1H4 (0.43) | ALDH1A1KDM4EHTTKMT2ALMNA | |
| SCHEMBL1058430 | 0.77 | HDAC1 (0.62) | KDM4ELMNANPC1USP2 | |
| SCHEMBL8917255 | 0.74 | ALDH1A1 (0.76) | ALDH1A1KDM4EHTTTDP1KMT2A | |
| SCHEMBL8914869 | 0.72 | ALDH1A1 (0.72) | ALDH1A1KDM4EHTTTDP1KMT2A | |
| SCHEMBL7933991 | 0.71 | ALDH1A1 (0.72) | ALDH1A1KDM4EHTTTDP1KMT2A | |
| SCHEMBL3142795 | 0.71 | ALDH1A1 (0.72) | ALDH1A1KDM4EHTTTDP1KMT2A | |
| SCHEMBL1064531 | 0.71 | ALDH1A1 (0.71) | ALDH1A1KDM4EHTTTDP1KMT2A | |
| SCHEMBL27663681 | 0.71 | ALDH1A1 (0.70) | ALDH1A1KDM4EHTTTDP1KMT2A | |
| SCHEMBL8913178 | 0.71 | ALDH1A1 (0.71) | ALDH1A1KDM4EHTTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595343-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2009-09-29 | — | — | US | disclosed |