Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13741165 | 0.90 | MEN1 (0.45) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL13713834 | 0.85 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL14473923 | 0.78 | KDM4E (0.49) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL20281019 | 0.75 | KDM4E (0.46) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL5622863 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| Trifluoroacetic Acid SCHEMBL5622861 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL869935 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL15539797 | 0.72 | CTSS (0.43) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL12920147 | 0.72 | ALDH1A1 (0.49) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5429225 | 0.71 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579324-B2 | Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof | C-A-I-R BIOSCIENCES GMBH (DE) | 2009-08-25 | — | — | US | disclosed |