Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.43 |
| ▸ | CTSK | P43235 | 10/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622971 | 0.79 | MEN1 (0.60) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16715180 | 0.74 | KDM4E (0.49) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16715181 | 0.74 | KDM4E (0.49) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL13713834 | 0.74 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL13713840 | 0.72 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7281071 | 0.71 | ACE (0.48) | CTSSCTSKACESMN1; SMN2ITGA4 | |
| SCHEMBL13741165 | 0.71 | MEN1 (0.45) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL20281115 | 0.70 | SLC17A5 (0.61) | MEN1KMT2A | |
| SCHEMBL31327597 | 0.70 | AAK1 (0.48) | CTSSCTSKACEITGA4ITGB7 | |
| SCHEMBL8650368 | 0.70 | SCN9A (0.52) | CTSSCTSKMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013188607-A1 | ONE STEP N-TERMINAL TAGGING OF PROTEINS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013188635-A2 | NOVEL METHODS OF IDENTIFYING PROTEINS VIA N-TERMINAL TAGGING AND SELECTIVE PULL-DOWN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-12-19 | — | — | WO | disclosed |