Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.37 |
| ▸ | CBFB | Q13951 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028919 | 0.80 | TYR (0.37) | ALDH1A1MAPTGAAHPGDHTT | |
| Deferitrin SCHEMBL1272026 | 0.80 | TYR (0.35) | ALDH1A1MAPTGAAHPGDHTT | |
| Deferitrin SCHEMBL18103545 | 0.80 | TYR (0.35) | ALDH1A1MAPTGAAHPGDHTT | |
| Deferitrin SCHEMBL663744 | 0.80 | TYR (0.35) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL14028916 | 0.80 | TYR (0.37) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL28043436 | 0.78 | TYR (0.35) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL28026304 | 0.78 | TYR (0.36) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL10330713 | 0.78 | HSP90AA1 (0.37) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL4952161 | 0.77 | TYR (0.35) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL18103523 | 0.76 | TYR (0.32) | ALDH1A1MAPTGAAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576234-B2 | Michael-type addition of a nucleophile to a dialkyl 2-methylidenylpropan-1,3-dioate and the conversion of a ester moiety into an amino moiety; S)-2-methylcysteine; desferrithiocin | GENZYME CORPORATION (US) | 2009-08-18 | — | — | US | disclosed |
| US-7294718-B2 | Synthesis of a 4-methylthiazole-4(S)-carboxylic acid compound | GENZYME CORPORATION (US) | 2007-11-13 | — | — | US | disclosed |
| US-7285676-B2 | Synthesis of chiral 2-alkyl amino acids | GENZYME CORPORATION (US) | 2007-10-23 | — | — | US | disclosed |
| US-7285670-B2 | Synthesis of substituted thiazoline carboxylic acids | GENZYME CORPORATION (US) | 2007-10-23 | — | — | US | disclosed |