SCHEMBL28026304

SCHEMBL28026304

C[C@]1(OC(=O)O[C@@]2(C)CSC(c3ccc(O)cc3O)=N2)CSC(c2ccc(O)cc2O)=N1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 5/20 0.36
ALDH1A1 P00352 3/20 0.34
GAA P10253 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
HTT P42858 2/20 0.34
RUNX1 Q01196 1/20 0.34
CBFB Q13951 1/20 0.34
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA7 P43166 3/20 0.33
CA9 Q16790 3/20 0.33
CA14 Q9ULX7 3/20 0.33
PDK2 Q15119 1/20 0.33
PDK4 Q16654 1/20 0.33
AMY1A P0DUB6 1/20 0.32
KDM4E B2RXH2 2/20 0.32
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4952161 0.91 TYR (0.35) TYRALDH1A1GAAMAPTHPGD
SCHEMBL28067847 0.87 HSP90AB1 (0.35) TYRALDH1A1GAAMAPTHTT
SCHEMBL28043436 0.84 TYR (0.35) TYRALDH1A1GAAMAPTHPGD
SCHEMBL13714599 0.78 ALDH1A1 (0.37) TYRALDH1A1GAAMAPTHPGD
SCHEMBL6985974 0.78 KDM4E (0.37) ALDH1A1GAAMAPTHPGDHTT
SCHEMBL14028919 0.78 TYR (0.37) TYRALDH1A1GAAMAPTHPGD
Deferitrin SCHEMBL1272026 0.78 TYR (0.35) TYRALDH1A1GAAMAPTHPGD
SCHEMBL14028916 0.78 TYR (0.37) TYRALDH1A1GAAMAPTHPGD
Deferitrin SCHEMBL663744 0.78 TYR (0.35) TYRALDH1A1GAAMAPTHPGD
Deferitrin SCHEMBL18103545 0.78 TYR (0.35) TYRALDH1A1GAAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103435569-B Denitrogenation as metal chelator is mixed the new salts of Desferrithiocin polyether analogues and polymorphic form FERROKIN BIOSCIENCES INC (US) 2015-08-19 CN disclosed