Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330712 | 0.96 | OPRK1 (0.37) | HSP90AA1HSP90AB1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12526907 | 0.96 | OPRK1 (0.37) | HSP90AA1HSP90AB1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11963215 | 0.85 | SLC22A12 (0.39) | HSP90AA1HSP90AB1CHEK2BACE1SLC22A12 | |
| SCHEMBL12526863 | 0.85 | PDK2 (0.34) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18499304 | 0.85 | MAOB (0.35) | HSP90AA1HSP90AB1CHEK2BACE1SLC22A12 | |
| SCHEMBL18197371 | 0.83 | PDK2 (0.42) | — | |
| SCHEMBL18499305 | 0.82 | OPRK1 (0.36) | HSP90AA1HSP90AB1CHEK2BACE1MIF | |
| SCHEMBL11963323 | 0.82 | SLC22A12 (0.37) | CHEK2BACE1MIFSLC22A12OPRK1 | |
| SCHEMBL16975985 | 0.82 | OPRK1 (0.36) | HSP90AA1HSP90AB1CHEK2BACE1MIF | |
| SCHEMBL11963439 | 0.82 | SLC22A12 (0.37) | CHEK2BACE1MIFSLC22A12OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190106-A1 | DESFERRITHIOCIN POLYETHER ANALOGUES | University of Florida Research Foundation, Inc. (US) | 2017-07-12 | — | — | EP | disclosed |
| US-20120184586-A1 | DESFERRITHIOCIN POLYETHER ANALOGUES AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184586-A1 | DESFERRITHIOCIN POLYETHER ANALOGUES AND USES THEREOF | TFRC, FTH1, TTPA | HSP90AA1 1214/4885HSP90AB1 1151/4885NPC1 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.