Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FER | P16591 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13714609 | 0.93 | AR (0.46) | ARCSNK2A1CLK4JAK2PRKD3 | |
| SCHEMBL13714563 | 0.82 | ALDH1A1 (0.54) | ARCSNK2A1CLK4JAK2PRKD3 | |
| SCHEMBL13714837 | 0.75 | AR (0.52) | AREGFRALDH1A1NPY5RTP53 | |
| SCHEMBL3860803 | 0.74 | CYP3A4 (0.47) | ARCSNK2A1CLK4JAK2PRKD3 | |
| SCHEMBL13714602 | 0.74 | HSD17B10 (0.50) | ARCSNK2A1CLK4JAK2PRKD3 | |
| SCHEMBL9748435 | 0.73 | ALDH1A1 (0.59) | ARMKNK2ALDH1A1TP53ALOX15 | |
| SCHEMBL13714838 | 0.73 | RAB9A (0.56) | ARCSNK2A1CLK4JAK2PRKD3 | |
| SCHEMBL13714593 | 0.71 | MAPT (0.50) | ARCSNK2A1CLK4JAK2PRKD3 | |
| SCHEMBL13714604 | 0.71 | RAB9A (0.50) | ARCSNK2A1CLK4JAK2PRKD3 | |
| SCHEMBL17014767 | 0.70 | AR (0.74) | ARALDH1A1TP53ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569596-B2 | Imidazolamino compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-08-04 | — | — | US | disclosed |
| US-7569596-B2 | Imidazolamino compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-08-04 | — | — | US | disclosed |
| US-7462723-B2 | Imidazolamino compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-12-09 | — | — | US | disclosed |
| US-7462723-B2 | Imidazolamino compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-12-09 | — | — | US | disclosed |