Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100886 | 0.85 | HTR2A (0.46) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL14667559 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL27911679 | 0.81 | GPR84 (0.59) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL28938665 | 0.79 | ALDH1A1 (0.55) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL31302644 | 0.79 | ALDH1A1 (0.55) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL1137607 | 0.79 | PARP1 (0.51) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL13715349 | 0.78 | HTT (0.54) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL4223523 | 0.77 | MPO (0.58) | ALDH1A1LMNAHTTMAPTHTR2A | |
| SCHEMBL31607554 | 0.77 | TRIM24 (0.60) | RENMAPTHTR2AATMSMN1; SMN2 | |
| SCHEMBL2143637 | 0.77 | TRIM24 (0.60) | RENMAPTHTR2AATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214458-A2 | ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | ABBVIE INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| CN-103214408-B | A kind of method of synthesizing bisindole methane derivative | NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-09-30 | — | — | CN | disclosed |
| CN-103214408-A | Method for synthesizing bisindole methane derivative | UNIV NANJING SCIENCE & TECH | 2013-07-24 | — | — | CN | disclosed |
| EP-1465880-B1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE TO TREAT DISORDERS ASSOCIATED WITH SOMATOSTATINE | IPSEN PHARMA (FR) | 2009-08-05 | — | — | EP | disclosed |