Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 9/20 | 0.46 |
| ▸ | HTR2C | P28335 | 6/20 | 0.45 |
| ▸ | HTR2B | P41595 | 5/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19604558 | 0.86 | GPR84 (0.73) | GPR84SLC6A4HTR1AHTR2AHTR2C | |
| SCHEMBL26285351 | 0.83 | HTR1A (0.70) | GPR84SLC6A4HTR1AHTR2AHTR2C | |
| SCHEMBL4220443 | 0.83 | GPR84 (0.69) | GPR84SLC6A4HTR1AHTR2AHTR2C | |
| SCHEMBL2533008 | 0.83 | GPR84 (0.69) | GPR84SLC6A4HTR1AHTR2AHTR2C | |
| SCHEMBL11273551 | 0.83 | GPR84 (0.69) | GPR84SLC6A4HTR1AHTR2AHTR2C | |
| SCHEMBL24243710 | 0.82 | HTR2A (0.63) | GPR84SLC6A4HTR1AHTR2AHTR2C | |
| SCHEMBL8543544 | 0.82 | SLC6A4 (0.83) | GPR84SLC6A4HTR1AHTR2AHTR2C | |
| SCHEMBL24243679 | 0.82 | SLC6A4 (0.68) | GPR84SLC6A4HTR1AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL21546036 | 0.81 | GPR84 (0.67) | GPR84SLC6A4HTR1AHTR2AHTR2C | |
| SCHEMBL13715392 | 0.81 | GPR84 (0.71) | GPR84SLC6A4HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465880-B1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE TO TREAT DISORDERS ASSOCIATED WITH SOMATOSTATINE | IPSEN PHARMA (FR) | 2009-08-05 | — | — | EP | disclosed |