Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.69 |
| ▸ | HTR2A | P28223 | 8/20 | 0.68 |
| ▸ | HTR2C | P28335 | 4/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.54 |
| ▸ | HTR1D | P28221 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21546036 | 0.98 | GPR84 (0.67) | GPR84HTR2AHTR2CSLC6A4TAAR1 | |
| Oxalic Acid SCHEMBL2533945 | 0.91 | HTR2C (0.60) | GPR84HTR2AHTR2CSLC6A4TAAR1 | |
| SCHEMBL11273551 | 0.83 | GPR84 (0.69) | GPR84HTR2AHTR2CSLC6A4HTR1D | |
| SCHEMBL4220443 | 0.83 | GPR84 (0.69) | GPR84HTR2AHTR2CSLC6A4HTR1D | |
| SCHEMBL13715344 | 0.83 | GPR84 (0.69) | GPR84HTR2AHTR2CSLC6A4HTR1D | |
| SCHEMBL7854823 | 0.81 | HTR2A (0.56) | GPR84HTR2AHTR2CTAAR1HTR1D | |
| SCHEMBL1971620 | 0.81 | HTR2A (1.00) | GPR84HTR2AHTR2CSLC6A4TAAR1 | |
| SCHEMBL26185612 | 0.81 | HTR2A (0.70) | GPR84HTR2AHTR2CSLC6A4TAAR1 | |
| SCHEMBL16540125 | 0.80 | SLC6A4 (0.67) | GPR84HTR2AHTR2CSLC6A4HTR1D | |
| Hydrochloric Acid SCHEMBL21546052 | 0.79 | HTR2A (0.97) | GPR84HTR2AHTR2CSLC6A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210108238-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | HERCULES CAPITAL, INC. | 2021-04-15 | — | — | US | claimed |
| EP-3762498-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | New Atlas Biotechnologies LLC (US) | 2021-01-13 | — | — | EP | claimed |
| CN-112105734-A | Method for producing tryptamine | 新图集生物技术有限责任公司 | 2020-12-18 | — | — | CN | claimed |
| WO-2019173797-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | NEW ATLAS BIOTECHNOLOGIES LLC (US) | 2019-09-12 | — | — | WO | claimed |
| US-12595497-B2 | Processes for the production of tryptamines | COMPASS PATHFINDER LIMITED (GB) | 2026-04-07 | — | — | US | disclosed |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | UNIV DANMARKS TEKNISKE (DK) | 2025-11-20 | — | — | US | disclosed |
| CN-118546085-B | Plant disease control composition, preparation method and application thereof | 西北农林科技大学深圳研究院 | 2024-12-03 | — | — | CN | disclosed |
| CN-118546085-A | Plant disease control composition, preparation method and application thereof | 西北农林科技大学深圳研究院 | 2024-08-27 | — | — | CN | disclosed |
| US-20240084344-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | COMPASS PATHFINDER LIMITED (GB) | 2024-03-14 | — | — | US | disclosed |
| US-11661617-B2 | Processes for the production of tryptamines | COMPASS PATHFINDER LIMITED (GB) | 2023-05-30 | — | — | US | disclosed |
| CN-115850269-A | Tetrahydro-beta-carboline compound and preparation method and application thereof | 南京工业大学 | 2023-03-28 | — | — | CN | disclosed |
| US-11136293-B2 | Processes for the production of tryptamines | NEW ATLAS BIOTECHNOLOGIES LLC (US) | 2021-10-05 | — | — | US | disclosed |
| EP-1859798-A1 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | ELI LILLY AND COMPANY (US) | 2007-11-28 | — | — | EP | disclosed |
| EP-1379239-B1 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | LILLY CO ELI (US) | 2007-09-12 | — | — | EP | disclosed |
| US-20070099909-A1 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | CHEN ZHAOGEN | 2007-05-03 | — | — | US | disclosed |
| US-7157488-B2 | N-(2-Arylethyl) benzylamines as antagonists of the 5-HT6 receptor | ELI LILLY AND COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-20060009511-A9 | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor | CHEN ZHAOGEN | 2006-01-12 | — | — | US | disclosed |
| CN-1610547-A | N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor | LILLY CO ELI (US) | 2005-04-27 | — | — | CN | disclosed |
| EP-1379239-A2 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | ELI LILLY AND COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002078693-A2 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | ELI LILLY AND COMPANY (US) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009511-A9 | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor | HTR6, HTR2C, HTR1B | GPR84 125/4885HTR2A 5/4885HTR2C 2/4885 |
| US-12595497-B2 | Processes for the production of tryptamines | INMT, TPH1, TPH2 | GPR84 2157/4885HTR2A 67/4885HTR2C 38/4885 |
| US-11661617-B2 | Processes for the production of tryptamines | TPH1, TPH2, AANAT | GPR84 1334/4885HTR2A 38/4885HTR2C 153/4885 |
| US-20240084344-A1 | PROCESSES FOR THE PRODUCTION OF TRYPTAMINES | TPH1, TPH2, AANAT | GPR84 1334/4885HTR2A 38/4885HTR2C 153/4885 |
| US-11136293-B2 | Processes for the production of tryptamines | TPH1, TPH2, AANAT | GPR84 1334/4885HTR2A 38/4885HTR2C 153/4885 |
| US-20070099909-A1 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | HTR6, HTR2C, HTR1B | GPR84 125/4885HTR2A 5/4885HTR2C 2/4885 |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | INMT, KARS1, MIA3 | GPR84 3005/4885HTR2A 2339/4885HTR2C 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.