Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.67 |
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | MPO | P05164 | 8/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454430 | 0.86 | GPR84 (0.71) | GPR84HTR1AMPOMTNR1AHTR2A | |
| SCHEMBL30346543 | 0.86 | GPR84 (0.62) | GPR84HTR1AMPOHTR1DHTR1B | |
| SCHEMBL24358682 | 0.85 | GPR84 (0.71) | GPR84HTR1AMPOHTR1DHTR1B | |
| SCHEMBL29206456 | 0.84 | HTR2A (0.63) | GPR84HTR1AMPOHTR1DHTR1B | |
| SCHEMBL30877226 | 0.84 | HTR2A (0.63) | GPR84HTR1AMPOHTR1DHTR1B | |
| SCHEMBL13715692 | 0.83 | GPR84 (0.69) | GPR84HTR1AMPOHTR1DHTR1B | |
| SCHEMBL2539018 | 0.83 | GPR84 (0.69) | GPR84HTR1AMPOHTR1DHTR1B | |
| SCHEMBL13497613 | 0.82 | GPR84 (0.46) | GPR84HTR1AMPOMTNR1AHTR2A | |
| SCHEMBL14961013 | 0.82 | MTNR1A (0.56) | GPR84HTR1AMPOHTR1DHTR1B | |
| SCHEMBL31158597 | 0.82 | HTR2A (0.57) | GPR84HTR1AMPOHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465880-B1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE TO TREAT DISORDERS ASSOCIATED WITH SOMATOSTATINE | IPSEN PHARMA (FR) | 2009-08-05 | — | — | EP | disclosed |