Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.71 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | MPO | P05164 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25058915 | 0.85 | GPR84 (0.65) | GPR84HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL21131333 | 0.85 | GPR84 (0.75) | GPR84HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL13715348 | 0.85 | GPR84 (0.67) | GPR84HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL30346543 | 0.82 | GPR84 (0.62) | GPR84HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL4633747 | 0.80 | MPO (0.68) | GPR84HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL4601401 | 0.79 | GPR84 (0.65) | GPR84HTR1AMTNR1AHTR2BHTR2A | |
| SCHEMBL8223121 | 0.79 | GPR84 (0.65) | GPR84HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL23259357 | 0.79 | GPR84 (0.65) | GPR84HTR1AHTR1DHTR1BHTR2B | |
| SCHEMBL8222885 | 0.79 | GPR84 (0.65) | GPR84HTR1AHTR1DHTR1BHTR2B | |
| SCHEMBL29445177 | 0.79 | GPR84 (0.65) | GPR84HTR1AHTR1DHTR1BHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | ME1, ME2, ME3 | GPR84 3768/4885HTR1A 4870/4885HTR1D 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.