Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.58 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064676 | 0.86 | ESR1 (0.72) | ESR1ESR2KIF11MMP3BCL2L1 | |
| SCHEMBL13050035 | 0.86 | ALDH1A1 (0.46) | ESR1ESR2KIF11NR1H2NR1H3 | |
| SCHEMBL13050033 | 0.86 | ALDH1A1 (0.46) | ESR1ESR2KIF11NR1H2NR1H3 | |
| SCHEMBL18874336 | 0.86 | ALDH1A1 (0.46) | ESR1ESR2KIF11NR1H2NR1H3 | |
| SCHEMBL2122016 | 0.82 | MMP3 (0.64) | ESR1ESR2MMP3BCL2L1ALDH1A1 | |
| SCHEMBL14964498 | 0.82 | MMP3 (0.64) | ESR1ESR2MMP3BCL2L1ALDH1A1 | |
| SCHEMBL10906373 | 0.82 | ESR1 (0.86) | ESR1ESR2KIF11MMP3BCL2L1 | |
| SCHEMBL21103544 | 0.82 | MMP3 (0.64) | ESR1ESR2MMP3BCL2L1ALDH1A1 | |
| SCHEMBL6059489 | 0.82 | ESR1 (0.86) | ESR1ESR2KIF11MMP3BCL2L1 | |
| SCHEMBL12603689 | 0.82 | MMP3 (0.64) | ESR1ESR2MMP3BCL2L1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362463-B2 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362463-B2 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-20090206327-A1 | ORGANOMETALLIC COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090206327-A1 | ORGANOMETALLIC COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090206327-A1 | ORGANOMETALLIC COMPLEXES | SLC25A11, TIMM9, TIMM50 | ESR1 3111/4885ESR2 3791/4885KIF11 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.