Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.72 |
| ▸ | MMP3 | P08254 | 1/20 | 0.60 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.60 |
| ▸ | KIF11 | P52732 | 2/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6059770 | 0.92 | ESR1 (0.86) | ESR1ESR2MMP3BCL2L1KIF11 | |
| SCHEMBL6059489 | 0.92 | ESR1 (0.86) | ESR1ESR2MMP3BCL2L1KIF11 | |
| SCHEMBL10906373 | 0.92 | ESR1 (0.86) | ESR1ESR2MMP3BCL2L1KIF11 | |
| SCHEMBL20920725 | 0.90 | ESR2 (0.58) | ESR1ESR2MMP3BCL2L1KIF11 | |
| SCHEMBL8488305 | 0.90 | ESR1 (0.82) | ESR1ESR2MMP3BCL2L1KIF11 | |
| Phenol SCHEMBL8427030 | 0.90 | ESR1 (0.82) | ESR1ESR2MMP3BCL2L1KIF11 | |
| SCHEMBL19033451 | 0.87 | KIF11 (0.62) | ESR1ESR2MMP3BCL2L1KIF11 | |
| SCHEMBL13715465 | 0.86 | ESR1 (0.58) | ESR1ESR2MMP3BCL2L1KIF11 | |
| SCHEMBL3686864 | 0.85 | ESR1 (1.00) | ESR1ESR2KIF11ALDH1A1CYP3A4 | |
| SCHEMBL4560440 | 0.85 | ESR1 (1.00) | ESR1ESR2KIF11ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1272884-A | Adipocyte-specific protein homologs | ZYMOGENETICS INC (US) | 2000-11-08 | — | — | CN | disclosed |
| CN-1263882-A | Method for preparing fluorine-substituted aromatic compound | MITSUI CHEMICALS INC (JP) | 2000-08-23 | — | — | CN | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |