Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17072005 | 0.87 | KDM4E (0.50) | KDM4EHSD17B10POLBCYP2C19ALDH1A1 | |
| SCHEMBL13715485 | 0.86 | KDM4E (0.58) | KDM4EHSD17B10POLBCYP2C19PDK1 | |
| SCHEMBL21722984 | 0.82 | KDM4E (0.54) | KDM4EHSD17B10POLBCYP2C19PDK1 | |
| SCHEMBL13715404 | 0.79 | KDM4E (0.50) | KDM4EHSD17B10POLBCYP2C19ALDH1A1 | |
| SCHEMBL7754189 | 0.77 | POLB (0.53) | KDM4EHSD17B10POLBALDH1A1NPC1 | |
| SCHEMBL217628 | 0.77 | TSHR (0.61) | KDM4EHSD17B10ALDH1A1MAPTMEN1 | |
| SCHEMBL32690872 | 0.77 | TSHR (0.61) | KDM4EHSD17B10ALDH1A1MAPTMEN1 | |
| SCHEMBL6207171 | 0.77 | KDM4E (0.46) | KDM4EHSD17B10POLBPDK1PDK2 | |
| SCHEMBL6750019 | 0.76 | KDM4E (0.75) | KDM4EHSD17B10ALDH1A1RAB9AMEN1 | |
| SCHEMBL670482 | 0.76 | CLCN2 (0.51) | KDM4EHSD17B10POLBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569723-B2 | Benzoic acid derivatives as non nucleoside reverse-transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| US-20080114068-A1 | BENZOIC ACID DERIVATIVES AS NON NUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114068-A1 | BENZOIC ACID DERIVATIVES AS NON NUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITORS | POLR2A, POLR1A, RTF1 | KDM4E 1619/4885HSD17B10 592/4885POLB 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.