Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1485604 | 0.98 | ALDH1A1 (0.37) | SMN1; SMN2ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL1485771 | 0.92 | MAPT (0.36) | SMN1; SMN2ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL11152589 | 0.91 | MAPT (0.43) | ALDH1A1MAPTBCHEACHE | |
| SCHEMBL8019345 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2ALOX15ALDH1A1HPGDRAB9A | |
| SCHEMBL1485859 | 0.86 | LMNA (0.37) | SMN1; SMN2ALOX15ALDH1A1HPGDMAPT | |
| SCHEMBL27831386 | 0.86 | — | — | |
| SCHEMBL10494003 | 0.83 | ALOX15 (0.38) | SMN1; SMN2ALOX15ALDH1A1KDM4E | |
| SCHEMBL24087422 | 0.80 | ALOX15 (0.38) | SMN1; SMN2ALOX15ALDH1A1RAB9APKM | |
| SCHEMBL1485782 | 0.80 | ALOX15 (0.38) | SMN1; SMN2ALOX15ALDH1A1RAB9APKM | |
| SCHEMBL1485781 | 0.80 | ALOX15 (0.38) | SMN1; SMN2ALOX15ALDH1A1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357111-B1 | 2-PYRIDONE DERIVATIVES HAVING AFFINITY FOR CANNABINOID TYPE 2 RECEPTOR | SHIONOGI & CO (JP) | 2009-08-05 | — | — | EP | disclosed |