Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | DNTT | P04053 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13716632 | 0.99 | SOAT1 (0.35) | SOAT1HPGD | |
| SCHEMBL13716586 | 0.99 | SOAT1 (0.35) | SOAT1HPGD | |
| SCHEMBL13716530 | 0.96 | SOAT1 (0.36) | SOAT1HPGD | |
| SCHEMBL13716589 | 0.90 | SOAT1 (0.37) | SOAT1 | |
| SCHEMBL9008090 | 0.80 | SOAT1 (0.35) | SOAT1 | |
| SCHEMBL9008099 | 0.77 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL9008076 | 0.76 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL9008080 | 0.76 | SOAT1 (0.35) | SOAT1 | |
| SCHEMBL8317765 | 0.76 | SOAT1 (0.47) | SOAT1HPGD | |
| SCHEMBL8325945 | 0.76 | SOAT1 (0.47) | SOAT1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569590-B2 | Use of thianecarboxamides as dgat inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-04 | — | — | US | disclosed |
| US-7569590-B2 | Use of thianecarboxamides as dgat inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-04 | — | — | US | disclosed |
| US-20080090876-A1 | USE OF THIANECARBOXAMIDES AS DGAT INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-17 | — | — | US | disclosed |
| US-20080090876-A1 | USE OF THIANECARBOXAMIDES AS DGAT INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090876-A1 | USE OF THIANECARBOXAMIDES AS DGAT INHIBITORS | DGAT1, DGAT2, DLAT | SOAT1 7/4885GPR84 323/4885HPGD 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.