Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4230443 | 0.89 | DDX3X (0.65) | GAAALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL20093477 | 0.84 | GAA (0.57) | GAAALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL1242082 | 0.83 | NPSR1 (0.69) | GAAALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL12825257 | 0.83 | NPSR1 (0.65) | GAAALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL20332958 | 0.82 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2LMNANPSR1USP2 | |
| SCHEMBL4218895 | 0.82 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2LMNANPSR1USP2 | |
| SCHEMBL10113100 | 0.81 | NPY5R (0.53) | GAAALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL10113954 | 0.81 | GRIA2 (0.53) | GAAALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL13203720 | 0.81 | NPY5R (0.53) | GAAALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL12825253 | 0.80 | ALDH1A1 (0.54) | GAAALDH1A1SMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1249233-B9 | NPYY5 ANTAGONISTS | SHIONOGI & CO (JP) | 2009-08-05 | — | — | EP | disclosed |
| EP-1249233-B1 | NPYY5 ANTAGONISTS | SHIONOGI & CO (JP) | 2008-08-20 | — | — | EP | disclosed |