Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14553749 | 0.80 | TRPA1 (0.46) | TRPA1ALDH1A1ALOX15HSD17B10TP53 | |
| SCHEMBL13463122 | 0.79 | ALDH1A1 (0.42) | ALDH1A1ALOX15TP53TDP1CA1 | |
| SCHEMBL10292484 | 0.76 | TRPA1 (0.56) | TRPA1ALDH1A1ALOX15HSD17B10TP53 | |
| SCHEMBL806486 | 0.76 | ALDH1A1 (0.36) | ALDH1A1CA1CA2CA9LMNA | |
| SCHEMBL6441756 | 0.76 | AR (0.43) | TRPA1ALDH1A1ALOX15HSD17B10TP53 | |
| SCHEMBL6442340 | 0.76 | ALDH1A1 (0.43) | TRPA1ALDH1A1ALOX15HSD17B10TP53 | |
| SCHEMBL29398758 | 0.74 | ACHE (0.62) | TRPA1ALDH1A1ALOX15TP53TDP1 | |
| SCHEMBL218637 | 0.74 | ACHE (0.62) | TRPA1ALDH1A1ALOX15TP53TDP1 | |
| SCHEMBL13971412 | 0.72 | TRPA1 (0.52) | TRPA1ALDH1A1ALOX15HSD17B10TP53 | |
| SCHEMBL3371911 | 0.71 | TRPA1 (0.45) | TRPA1ALDH1A1ALOX15HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427415-B1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-08-12 | — | — | EP | disclosed |