SCHEMBL137181

SCHEMBL137181

CC(C)=CCCC(C)=CCCC(C)=CC(O)[GaH2]

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.61
MAPT P10636 2/20 0.55
MEN1 O00255 2/20 0.55
CYP3A4 P08684 2/20 0.55
ALOX15 P16050 2/20 0.55
ALDH1A1 P00352 1/20 0.55
UGT1A1 P22309 1/20 0.55
SQLE Q14534 7/20 0.53
KDM4E B2RXH2 2/20 0.50
FNTA P49354 1/20 0.50
FNTB P49356 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6664660 0.83 KMT2A (0.67) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL28679144 0.80 KMT2A (0.61) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL11529352 0.80 KMT2A (0.61) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL11670568 0.80 KMT2A (0.61) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL4585540 0.80 KMT2A (0.61) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL11620625 0.80 KMT2A (0.61) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL11584608 0.79 KMT2A (0.58) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL11586065 0.79 KMT2A (0.58) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL356392 0.79 KMT2A (0.58) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL23802597 0.78 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083773-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT EPIZON PHARMA INC (US) 2026-03-26 US disclosed
US-12514871-B2 Pegylated menaquinol compositions and methods of treatment Epizon Pharma, Inc. (US) 2026-01-06 US disclosed
WO-2023235259-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT Epizon Pharma, Inc. (US) 2023-12-07 WO disclosed
US-20230381220-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT Epizon Pharma, Inc. (US) 2023-11-30 US disclosed
US-11083685-B2 Methods for treating scars and aging skin ALLERGAN, INC. (US) 2021-08-10 US disclosed
US-10398640-B2 Methods for treating scars and aging skin ALLERGAN, INC. 2019-09-03 US disclosed
US-20180085392-A1 CYCLODEXTRIN COMPOUNDS FOR THE PREVENTION AND TREATMENT OF AGING SENS RES FOUNDATION INC (US) 2018-03-29 US disclosed
WO-2016168772-A1 CYCLODEXTRIN COMPOUNDS FOR THE PREVENTION AND TREATMENT OF AGING SENS RESEARCH FOUNDATION, INC. (US) 2016-10-20 WO disclosed
US-20160058816-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN, INC. 2016-03-03 US disclosed
US-20160058693-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN INC (US) 2016-03-03 US disclosed
US-9180157-B2 Methods for treating scars and aging skin ALLERGAN, INC. 2015-11-10 US disclosed
US-9180158-B2 Methods for treating scars and aging skin ALLERGAN, INC. 2015-11-10 US disclosed
US-20130337088-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN, INC. 2013-12-19 US disclosed
US-8591961-B2 Aesthetic treatment of scars and aging skin ALLERGAN, INC. (US) 2013-11-26 US disclosed
US-20120058167-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN, INC. 2012-03-08 US disclosed
US-20120058076-A1 AESTHETIC TREATMENT OF SCARS AND AGING SKIN ALLERGAN, INC. 2012-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180085392-A1 CYCLODEXTRIN COMPOUNDS FOR THE PREVENTION AND TREATMENT OF AGING CLN6, GBA2, GLA KMT2A 4663/4885MAPT 1920/4885MEN1 3599/4885
US-20230381220-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT PHOSPHO1, MEN1, MDH2 KMT2A 1923/4885MAPT 1887/4885MEN1 2/4885
US-20260083773-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT SGMS1, SGMS2, MEN1 KMT2A 1966/4885MAPT 4296/4885MEN1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.