Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13718890 | 0.85 | TSHR (0.56) | TSHRHDAC8HDAC6LMNAHDAC2 | |
| SCHEMBL14508383 | 0.77 | TSHR (0.65) | TSHRHDAC8HDAC6HDAC3ALDH1A1 | |
| SCHEMBL14210116 | 0.70 | HPGD (0.50) | TSHRHDAC8HDAC6LMNAHDAC3 | |
| SCHEMBL13718488 | 0.69 | TSHR (0.84) | TSHRHDAC8HDAC6LMNAHDAC2 | |
| SCHEMBL5675604 | 0.67 | SLC2A1 (0.53) | TSHRHDAC8HDAC6LMNAALDH1A1 | |
| SCHEMBL28328422 | 0.66 | TSHR (0.72) | TSHRHDAC8HDAC6HDAC2ALDH1A1 | |
| SCHEMBL13501297 | 0.66 | MMP13 (0.61) | HDAC8HDAC6HDAC2KMT2ASMN1; SMN2 | |
| SCHEMBL11900328 | 0.66 | HDAC6 (0.87) | HDAC8HDAC6HDAC2HDAC3ALDH1A1 | |
| SCHEMBL3029989 | 0.66 | CFD (0.69) | HDAC8HDAC6HDAC2ALDH1A1HSD17B10 | |
| SCHEMBL7086238 | 0.66 | TSHR (0.54) | TSHRLMNAALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089988-B1 | FLUOROPHENYL RESIN COMPOUNDS | AVENTIS PHARMA INC (US) | 2009-08-12 | — | — | EP | disclosed |