Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105 | 0.97 | ALDH1A1 (0.53) | ALDH1A1LPAR1MAPTHPGDNPSR1 | |
| SCHEMBL1279 | 0.83 | CYP1A2 (0.43) | ALDH1A1LPAR1MAPTKMT2AMEN1 | |
| SCHEMBL7013 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LPAR1NPSR1KMT2AMEN1 | |
| SCHEMBL18597680 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LPAR1NPSR1KMT2AMEN1 | |
| SCHEMBL5869 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LPAR1NPSR1KMT2AMEN1 | |
| SCHEMBL14472 | 0.81 | LPAR1 (0.58) | ALDH1A1LPAR1MAPTHPGDKMT2A | |
| SCHEMBL11897018 | 0.77 | SMN1; SMN2 (0.49) | ALDH1A1LPAR1MAPTKMT2AMEN1 | |
| SCHEMBL14367 | 0.77 | LPAR1 (0.50) | ALDH1A1LPAR1MAPTHPGDKMT2A | |
| SCHEMBL3829 | 0.77 | P2RX7 (0.42) | MAPTCYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10078633 | 0.76 | LPAR1 (0.38) | ALDH1A1LPAR1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090573-B2 | Compounds as lysophosphatidic acid receptor antagonists | AMIRA PHARMACEUTICALS, INC. (US) | 2015-07-28 | — | — | US | disclosed |
| US-20120289522-A1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS INC. | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289522-A1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR4 | ALDH1A1 3726/4885LPAR1 1/4885MAPT 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.