SCHEMBL1279

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10078633	0.91	LPAR1 (0.38)	CYP1A2CYP3A4CYP2C9CYP2C19TDP1
	SCHEMBL13426	0.87	LMNA (0.42)	CYP1A2CYP3A4CYP2C9CYP2C19TDP1
	SCHEMBL11897018	0.86	SMN1; SMN2 (0.49)	LPAR1FFAR4PTPN1MEN1KMT2A
	SCHEMBL27868823	0.84	SMN1; SMN2 (0.40)	AURKAAURKBKDRPTPN1MEN1
	SCHEMBL27842851	0.84	PTGDR2 (0.43)	FFAR4AURKAAURKBKDRPOLB
	SCHEMBL27842838	0.83	AURKA (0.40)	TDP1LPAR1FFAR4AURKAAURKB
	SCHEMBL1555	0.83	HTT (0.45)	CYP1A2CYP3A4CYP2C9CYP2C19TDP1
	SCHEMBL3829	0.83	P2RX7 (0.42)	CYP1A2CYP3A4CYP2C9CYP2C19TDP1
	SCHEMBL13719968	0.83	ALDH1A1 (0.50)	CYP3A4CYP2C9CYP2C19LPAR1MEN1
	SCHEMBL1683	0.81	CYP1A2 (0.43)	CYP1A2CYP3A4CYP2C9CYP2C19TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.