Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13720972 | 0.81 | LIPE (0.49) | KMT2ARAB9AMEN1NPC1LIPE | |
| SCHEMBL13721740 | 0.75 | L3MBTL1 (0.46) | KMT2ARAB9AMEN1NPC1MAPT | |
| SCHEMBL3792617 | 0.67 | KMT2A (0.58) | KMT2ARAB9AMEN1NPC1PDK1 | |
| SCHEMBL1053651 | 0.67 | LIPE (0.49) | KMT2ARAB9AMEN1NPC1LIPE | |
| SCHEMBL14254880 | 0.66 | PDK1 (0.69) | KMT2ARAB9AMEN1NPC1PDK1 | |
| SCHEMBL31718129 | 0.66 | PDK1 (0.69) | KMT2ARAB9AMEN1NPC1PDK1 | |
| SCHEMBL1063614 | 0.66 | LIPE (0.49) | LIPEPDK1PDK2PDK3PDK4 | |
| SCHEMBL18088737 | 0.65 | POLB (0.58) | KMT2ARAB9AMEN1NPC1PDK1 | |
| SCHEMBL6993599 | 0.65 | KMT2A (0.55) | KMT2ARAB9AMEN1PDK1PDK2 | |
| SCHEMBL6992137 | 0.64 | KMT2A (0.56) | KMT2ARAB9AMEN1NPC1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012155042-A2 | NOVEL BORATE DERIVATIVES AND THEIR APPLICATIONS | ANDERSON DEVELOPMENT COMPANY (US) | 2012-11-15 | — | — | WO | disclosed |
| US-20120289733-A1 | NOVEL BORATE DERIVATIVES AND THEIR APPLICATIONS | ANDERSON DEVELOPMENT COMPANY (US) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289733-A1 | NOVEL BORATE DERIVATIVES AND THEIR APPLICATIONS | BRS3, BRSK1, CA4 | KMT2A 2803/4885RAB9A 1567/4885MEN1 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.