SCHEMBL13722137

B[C@@H]1O[C@@](CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)([C@@H](C)OS(C)(=O)=O)[C@@H](OC)[C@H]1OC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	SMYD2	Q9NRG4	1/20	0.31

▸	MMP9	P14780	1/20	0.31

▸	MMP12	P39900	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12306568	0.92	MMP9 (0.33)	SMYD2MMP9MMP12
SCHEMBL12306537	0.92	MMP9 (0.33)	SMYD2MMP9MMP12
SCHEMBL12306595	0.82	SMYD2 (0.33)	SMYD2MMP9MMP12
SCHEMBL12306624	0.82	SMYD2 (0.33)	SMYD2MMP9MMP12
SCHEMBL13722428	0.82	SMYD2 (0.30)	SMYD2
SCHEMBL12306600	0.78	ACHE (0.36)	—
SCHEMBL12306577	0.78	ACHE (0.36)	—
SCHEMBL12306555	0.78	SMYD2 (0.32)	SMYD2
SCHEMBL12306570	0.78	SMYD2 (0.32)	SMYD2
SCHEMBL12306554	0.77	PRMT6 (0.43)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7569686-B1	Compounds and methods for synthesis of bicyclic nucleic acid analogs	ISIS PHARMACEUTICALS, INC. (US)	2009-08-04	—	—	US	disclosed