SCHEMBL1372284

SCHEMBL1372284

OCC(O)COCC(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.41
HTT P42858 1/20 0.38
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
PLA2G2C Q5R387 1/20 0.33
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24824267 0.87 HTT (0.42) HTTLMNAALDH1A1PLA2G2CCYP2C9
SCHEMBL20227110 0.86 USP2 (0.41) USP2HTTLMNAALDH1A1THRB
SCHEMBL11953067 0.84 USP2 (0.39) USP2LMNAALDH1A1
SCHEMBL100711 0.82 USP2 (0.42) USP2LMNAALDH1A1
SCHEMBL21895581 0.82 THRB (0.39) HTTPLA2G2CCYP2C9TSHRCYP2C19
SCHEMBL18609453 0.81 PLA2G2C (0.39) USP2HTTPLA2G2CCYP2C9TSHR
SCHEMBL9873342 0.81 PLA2G2C (0.39) USP2HTTPLA2G2CCYP2C9TSHR
SCHEMBL9873857 0.81 HTT (0.38) HTTLMNAPLA2G2C
SCHEMBL15494110 0.80 USP2 (0.37) USP2LMNAALDH1A1
SCHEMBL21633295 0.80 USP2 (0.37) USP2HTTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3635022-B1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA TEC LTD (US) 2025-05-21 EP disclosed
CN-116354830-A Process for the preparation of functionalized fluorinated monomers, fluorinated monomers and compositions for the preparation thereof 埃特纳科技有限公司 2023-06-30 CN disclosed
CN-110770271-B Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2023-04-18 CN disclosed
US-11492318-B2 Methods for making functionalized fluorinated monomers, fluorinated monomers, and compositions for making the same ETNA-TEC, LTD. (US) 2022-11-08 US disclosed
US-20220213016-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ETNA-TEC, LTD. 2022-07-07 US disclosed
EP-3635022-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME Etna-Tec, Ltd (US) 2020-04-15 EP disclosed
US-20200102417-A1 STRETCHABLE FILM AND METHOD FOR FORMING STRETCHABLE FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-04-02 US disclosed
CN-110770271-A Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2020-02-07 CN disclosed
US-20200040125-A1 STRETCHABLE FILM AND METHOD FOR FORMING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-06 US disclosed
US-20180334417-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ETNA-TEC, LTD. 2018-11-22 US disclosed
US-20070148682-A1 Protein fragment complementation assays for the detection of biological or drug interactions ODYSSEY PHARMACEUTICALS, INC. (US) 2007-06-28 US disclosed
US-7169829-B2 Maleimido-bearing compounds resin composition containing the same and cured articles thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
US-7160691-B2 Protein fragment complementation assays for the detection of biological or drug interactions ODYSSEY THERA INC. (US) 2007-01-09 US disclosed
US-6929916-B2 Protein fragment complementation assays for the detection of biological or drug interactions ODYSSEY THERA INC. (US) 2005-08-16 US disclosed
US-20050079547-A1 Protein fragment complementation assays in whole animals applications to drug efficacy, ADME, cancer biology, immunology, infectious disease and gene therapy MICHNICK STEPHEN WILLIAM WATSO (CA) 2005-04-14 US disclosed
US-20050009947-A1 Maleimido-bearing compounds resin composition containing the same and cured articles thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-01-13 US disclosed
EP-1460092-A1 MALEIMIDO-BEARING COMPOUNDS, RESIN COMPOSITIONS CONTAINING THE SAME AND CURED ARTICLES THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2004-09-22 EP disclosed
US-6294330-B1 SCREENING LIGANDS OF CELLULAR RECEPTOR BY GENERATING VECTORS ENCODING FUSION PROTEINS OF FRAGMENTS OF REPORTER MOLECULE AND SUBDOMAINS OF RECEPTOR, TRANSFECTING CELLS WITH VECTORS, TESTING CELLS FOR REPORTER MOLECULE ACTIVITY ODYSSEY PHARMACEUTICALS INC. 2001-09-25 US disclosed
US-6270964-B1 POLYPEPTIDE USED A DIAGNOSTIC TOOL IN GENETIC ENGINEERING ODYSSEY PHARMACEUTICALS INC. 2001-08-07 US disclosed
EP-0254540-A2 Glycerol derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1988-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180334417-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ALKBH3, FTO, THEM6 USP2 2523/4885HTT 2042/4885LMNA 1217/4885
US-20220213016-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ALKBH3, FTO, ALK USP2 2470/4885HTT 2018/4885LMNA 1234/4885
US-11492318-B2 Methods for making functionalized fluorinated monomers, fluorinated monomers, and compositions for making the same ALKBH3, FTO, ALK USP2 2470/4885HTT 2018/4885LMNA 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.