Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 7/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724113 | 0.71 | ALB (0.42) | MEN1KMT2ATDP1ALDH1A1RAB9A | |
| SCHEMBL13147515 | 0.71 | ALB (0.42) | MEN1KMT2ATDP1ALDH1A1RAB9A | |
| SCHEMBL13725172 | 0.68 | MC4R (0.50) | MEN1KMT2AMC4R | |
| SCHEMBL21439307 | 0.68 | MAPK8 (0.44) | CD38MAPK8PARP1CYP3A4MEN1 | |
| SCHEMBL6221992 | 0.67 | MC4R (0.42) | L3MBTL1MC4RRAB9ASMN1; SMN2 | |
| SCHEMBL27722171 | 0.66 | MAPK8 (0.48) | CD38PBRM1MAPK8PARP1ALDH1A1 | |
| SCHEMBL27756491 | 0.66 | MAPK8 (0.48) | CD38PBRM1MAPK8PARP1CYP3A4 | |
| SCHEMBL28204604 | 0.66 | CD38 (0.45) | CD38MAPK8PARP1CYP3A4MEN1 | |
| SCHEMBL3089391 | 0.65 | MC4R (0.67) | MC4R | |
| SCHEMBL4661408 | 0.65 | TAAR1 (0.45) | CD38MAPK8PARP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |