Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 15/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13147515 | 0.79 | ALB (0.42) | NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL6222542 | 0.78 | MC4R (0.64) | MC4RKCNH2 | |
| SCHEMBL3090277 | 0.78 | MC4R (0.41) | MC4RNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL6222879 | 0.68 | MC4R (0.54) | MC4R | |
| SCHEMBL3080665 | 0.68 | MC4R (0.78) | MC4R | |
| SCHEMBL13723655 | 0.67 | L3MBTL1 (0.37) | MC4RL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL13724113 | 0.66 | ALB (0.42) | RAB9ASMN1; SMN2 | |
| SCHEMBL3082437 | 0.66 | KDM4E (0.43) | MC4RNPC1RAB9A | |
| SCHEMBL2560634 | 0.63 | NOS3 (0.44) | HPGDSMN1; SMN2 | |
| SCHEMBL29960836 | 0.61 | TAAR1 (0.52) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | Gene Logic Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004050610-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | GENE LOGIC INC. (US) | 2004-06-17 | — | — | WO | disclosed |