SCHEMBL1372389

SCHEMBL1372389

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 14/20 0.55
▸ OPRM1 P35372 8/20 0.55
▸ OPRK1 P41145 3/20 0.55
▸ MMP2 P08253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31222390 0.89 NPY4R (0.66) —
SCHEMBL31222395 0.89 NPY4R (0.66) —
SCHEMBL31222407 0.89 NPY4R (0.66) —
SCHEMBL1371080 0.89 OPRD1 (0.48) OPRD1OPRM1OPRK1MMP2
[Leu5]Enkephalin SCHEMBL29687098 0.88 OPRD1 (0.67) OPRD1OPRM1OPRK1
[Leu5]Enkephalin SCHEMBL17951964 0.88 OPRD1 (0.67) OPRD1OPRM1OPRK1
SCHEMBL31222375 0.87 NPY4R (0.68) —
SCHEMBL27849228 0.86 OPRD1 (0.48) OPRD1OPRM1OPRK1MMP2
Enkephalin SCHEMBL631958 0.82 OPRD1 (0.75) OPRD1OPRM1OPRK1
Enkephalin SCHEMBL16189980 0.82 OPRD1 (0.75) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC (CA) 2016-09-15 — — US disclosed
EP-2794663-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF Angiochem Inc. (CA) 2014-10-29 — — EP disclosed
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2011-11-24 — — US disclosed
WO-2010063124-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2010-06-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 OPRD1 4036/4885OPRM1 3822/4885OPRK1 3911/4885
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 OPRD1 4036/4885OPRM1 3822/4885OPRK1 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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