Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724991 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13724849 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13724846 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13725881 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13725309 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13724976 | 0.82 | LMNA (0.62) | ALDH1A1TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13724541 | 0.82 | LMNA (0.62) | ALDH1A1TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13724557 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL13724564 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL4093105 | 0.80 | SLC6A9 (0.42) | ALDH1A1LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215778-A1 | Alpha-substituted Arylmethyl Piperazine Pyrazolo [1,5-alpha]Pyrimidine Amide Derivatives | PANACOS PHARMACEUTICALS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215778-A1 | Alpha-substituted Arylmethyl Piperazine Pyrazolo [1,5-alpha]Pyrimidine Amide Derivatives | THPO, DPYD, TPMT | ALDH1A1 116/4885TSHR 4375/4885CYP2D6 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.