Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13725959 | 1.00 | ALDH1A1 (0.60) | ALDH1A1AKR1B10AKR1B1LMNATDP1 | |
| SCHEMBL5079339 | 0.90 | KMT2A (0.60) | ALDH1A1AKR1B10AKR1B1LMNATDP1 | |
| SCHEMBL5079340 | 0.90 | KMT2A (0.60) | ALDH1A1AKR1B10AKR1B1LMNATDP1 | |
| SCHEMBL81836 | 0.87 | LMNA (0.72) | ALDH1A1AKR1B10AKR1B1LMNATDP1 | |
| SCHEMBL81835 | 0.87 | LMNA (0.72) | ALDH1A1AKR1B10AKR1B1LMNATDP1 | |
| SCHEMBL12083357 | 0.85 | LMNA (0.56) | ALDH1A1AKR1B10AKR1B1LMNATDP1 | |
| SCHEMBL7221439 | 0.85 | LMNA (0.56) | ALDH1A1AKR1B10AKR1B1LMNATDP1 | |
| Methyl Alcohol SCHEMBL21995794 | 0.85 | LMNA (0.70) | ALDH1A1AKR1B10AKR1B1LMNATDP1 | |
| SCHEMBL30394688 | 0.83 | AKR1B10 (0.59) | ALDH1A1AKR1B10AKR1B1LMNATDP1 | |
| SCHEMBL30249969 | 0.83 | KMT2A (0.60) | ALDH1A1AKR1B10AKR1B1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012149604-A1 | BIS-THYMINE DERIVATIVES AND PHOTO-REVERSIBLE POLYMERS THEREOF | MONASH UNIVERSITY (AU) | 2012-11-08 | — | — | WO | disclosed |