Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | LPL | P06858 | 13/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12100235 | 0.83 | LPL (0.41) | EGFRLPLLIPGCSF1RCA1 | |
| SCHEMBL29591450 | 0.78 | LIPG (0.39) | EGFRLPLLIPGCSF1RCA1 | |
| SCHEMBL23218733 | 0.78 | LIPG (0.39) | EGFRLPLLIPGCSF1RCA1 | |
| SCHEMBL1805374 | 0.77 | ACHE (0.42) | EGFRLPLLIPGCSF1R | |
| SCHEMBL1343041 | 0.76 | LPL (0.47) | EGFRLPLLIPGCSF1RCA1 | |
| SCHEMBL23347163 | 0.76 | LPL (0.43) | EGFRLPLLIPGCSF1RCA1 | |
| SCHEMBL24564170 | 0.75 | AHR (0.49) | EGFRLPLLIPGCSF1R | |
| SCHEMBL419648 | 0.74 | LPL (0.48) | EGFRLPLLIPGCA1CA2 | |
| SCHEMBL24564177 | 0.74 | EGFR (0.46) | EGFRLPLLIPGCSF1R | |
| SCHEMBL18970215 | 0.73 | LPL (0.44) | EGFRLPLLIPGCSF1RCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2702043-A1 | INHIBITORS OF INDUCIBLE FORM OF 6-PHOSPHOFRUCTOSE-2-KINASE | Exelixis, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012149528-A1 | INHIBITORS OF INDUCIBLE FORM OF 6-PHOSPHOFRUCTOSE-2-KINASE | EXELIXIS, INC. (US) | 2012-11-01 | — | — | WO | disclosed |