Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000428 | 0.83 | HTR2C (0.46) | HTR2CHTR2BSRD5A2HTR6ALOX5 | |
| SCHEMBL1585413 | 0.82 | CHRM4 (0.45) | HTR2CHTR6ALOX5 | |
| SCHEMBL11785420 | 0.80 | SRD5A2 (0.46) | HTR2CHTR2BSRD5A2SMN1; SMN2KMT2A | |
| SCHEMBL13728722 | 0.78 | HTR6 (0.44) | HTR2CHTR2BSRD5A2HTR6ALOX5 | |
| SCHEMBL13727051 | 0.71 | LMNA (0.30) | LMNA | |
| SCHEMBL13727351 | 0.71 | HTR6 (0.37) | HTR2CHTR2BSRD5A2HTR6ALOX5 | |
| SCHEMBL27928499 | 0.70 | HTR2C (0.46) | HTR2CHTR2BHTR6LMNASMN1; SMN2 | |
| SCHEMBL11000504 | 0.69 | ESR1 (0.43) | HTR2CHTR2BL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8130252 | 0.69 | HTR2C (0.48) | HTR2CHTR2BHTR6 | |
| SCHEMBL5750728 | 0.69 | SORD (0.34) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |