Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 8/20 | 0.33 |
| ▸ | NPC1 | O15118 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362735 | 0.76 | CHRNA4 (0.39) | RAB9ANPC1KMT2ASMN1; SMN2CHRNA4 | |
| SCHEMBL13728573 | 0.75 | S1PR4 (0.36) | S1PR4RAB9ANPC1KMT2AMAPT | |
| SCHEMBL9512940 | 0.74 | HSD17B1 (0.51) | MAPTSMN1; SMN2TP53 | |
| SCHEMBL18920572 | 0.73 | KMT2A (0.50) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1694938 | 0.72 | LMNA (0.41) | S1PR4RAB9ANPC1KMT2AMAPT | |
| SCHEMBL3577961 | 0.72 | SMN1; SMN2 (0.47) | S1PR4RAB9ANPC1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL5352593 | 0.71 | SMN1; SMN2 (0.46) | S1PR4RAB9ANPC1KMT2AMAPT | |
| SCHEMBL9547540 | 0.71 | CES2 (0.39) | S1PR4RAB9ANPC1KMT2AMAPT | |
| SCHEMBL9483989 | 0.71 | ALOX5 (0.47) | S1PR4RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11722748 | 0.70 | CHRNA4 (0.36) | RAB9ANPC1CHRNA4RAPGEF3RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | S1PR4 4130/4885RAB9A 1714/4885NPC1 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.