Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 11/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 11/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13728281 | 0.88 | PRKCI (0.48) | PRMT6MKNK2GRM2PIM1 | |
| SCHEMBL13728047 | 0.86 | GRM2 (0.47) | GRM2MEN1 | |
| SCHEMBL13728270 | 0.81 | PRMT6 (0.45) | PRMT6BACE1 | |
| SCHEMBL13726397 | 0.80 | KCNA5 (0.43) | MKNK1MKNK2GRM2 | |
| SCHEMBL13728854 | 0.79 | NR3C2 (0.51) | — | |
| SCHEMBL30761107 | 0.76 | MKNK1 (0.59) | MKNK1MKNK2KMOMEN1PSIP1 | |
| SCHEMBL933914 | 0.76 | MKNK1 (0.59) | MKNK1MKNK2KMOMEN1PSIP1 | |
| SCHEMBL5252905 | 0.76 | NR3C2 (0.54) | — | |
| SCHEMBL13728612 | 0.76 | NR3C2 (0.54) | — | |
| SCHEMBL13729600 | 0.75 | P2RX3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |