Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 3/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | GPR52 | Q9Y2T5 | 11/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729921 | 0.84 | KMT2A (0.48) | NR3C2AURKARPS6KB1AURKBMAOB | |
| SCHEMBL13728854 | 0.81 | NR3C2 (0.51) | NR3C2AURKARPS6KB1HTR2CHTR2B | |
| SCHEMBL13728281 | 0.78 | PRKCI (0.48) | — | |
| SCHEMBL5252905 | 0.78 | NR3C2 (0.54) | NR3C2AURKARPS6KB1GPR52 | |
| SCHEMBL13729600 | 0.77 | P2RX3 (0.46) | — | |
| SCHEMBL13729128 | 0.76 | CHEK2 (0.45) | EPHX1 | |
| SCHEMBL1568281 | 0.76 | GPR52 (0.57) | NR3C2AURKARPS6KB1AURKBGPR52 | |
| SCHEMBL13728786 | 0.76 | EPHX2 (0.47) | — | |
| SCHEMBL13728192 | 0.75 | KMO (0.52) | AURKA | |
| SCHEMBL13728047 | 0.75 | GRM2 (0.47) | RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |