Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037845 | 0.84 | HTR6 (0.46) | HTR6ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL13727184 | 0.81 | HTR6 (0.43) | HTR6ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL13727904 | 0.80 | HTR6 (0.43) | HTR6ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL13729826 | 0.77 | HTR6 (0.47) | HTR6ALDH1A1TAAR1LTA4HAR | |
| SCHEMBL11782288 | 0.76 | BRS3 (0.47) | ALDH1A1LMNAKDM4E | |
| SCHEMBL3296809 | 0.75 | IDO1 (0.61) | L3MBTL1ALDH1A1IDO1TAAR1LMNA | |
| SCHEMBL31037839 | 0.75 | DHPS (0.43) | HTR6L3MBTL1ALDH1A1TSHRMAPK1 | |
| SCHEMBL16900008 | 0.75 | TSHR (0.47) | HTR6L3MBTL1ALDH1A1IDO1TAAR1 | |
| SCHEMBL20212358 | 0.74 | HTR6 (0.51) | HTR6ALDH1A1IDO1TAAR1LMNA | |
| SCHEMBL31037840 | 0.74 | DHPS (0.48) | HTR6L3MBTL1ALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |