Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | DHPS | P49366 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037839 | 0.90 | DHPS (0.43) | HTR6DHPSLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL31037844 | 0.89 | DHPS (0.43) | HTR6DHPSLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL31037840 | 0.89 | DHPS (0.48) | HTR6DHPSL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL31037841 | 0.85 | DHPS (0.62) | DHPSADORA3ADORA1LMNASMN1; SMN2 | |
| SCHEMBL13729249 | 0.84 | HTR6 (0.50) | HTR6ADORA3ADORA2AADORA1LMNA | |
| SCHEMBL31037825 | 0.82 | DHPS (0.62) | HTR6DHPSADORA3ADORA2AADORA1 | |
| SCHEMBL31037843 | 0.82 | DHPS (0.52) | DHPSADORA3LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7483960 | 0.79 | HTT (0.48) | DHPSLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL31037849 | 0.79 | DHPS (0.49) | HTR6DHPSADORA2ALMNASMN1; SMN2 | |
| SCHEMBL7854304 | 0.79 | DHPS (0.49) | HTR6DHPSADORA1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666758-A | Anti-melanoma benzyl pyrimidine compound and preparation method and application thereof | 中国医科大学附属盛京医院 | 2024-09-20 | — | — | CN | disclosed |