Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13728407 | 0.92 | HPGD (0.50) | NAAASMN1; SMN2NPC1RAB9ADRD2 | |
| SCHEMBL13824115 | 0.83 | SMN1; SMN2 (0.46) | NAAATSHRHTTSMN1; SMN2NPC1 | |
| SCHEMBL13824143 | 0.81 | POLB (0.46) | SMN1; SMN2NPC1RAB9AGAAKDM4E | |
| SCHEMBL5113449 | 0.80 | HPGDS (0.56) | HPGDS | |
| SCHEMBL13823951 | 0.79 | GABRG2 (0.51) | GAAHPGDKDM4EALDH1A1 | |
| SCHEMBL22543093 | 0.77 | ACP1 (0.52) | NAAATSHRHTTSMN1; SMN2NPC1 | |
| SCHEMBL13727381 | 0.76 | HTT (0.43) | NAAATSHRHTTSMN1; SMN2NPC1 | |
| SCHEMBL13726774 | 0.76 | TP53 (0.42) | NAAAHTTSMN1; SMN2DRD2DRD4 | |
| SCHEMBL13727863 | 0.75 | ALDH1A1 (0.49) | TSHRHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5114522 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |