SCHEMBL13729487

SCHEMBL13729487

O=C(O)N(C1=C\C=C\C=C/C=C/C=C/N/C=C/C=C\1)C1=C\C=C\C=C/C=C/C=C/N/C=C/C=C\1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16718037 0.81
SCHEMBL28298534 0.71
SCHEMBL27761336 0.67
SCHEMBL28299873 0.65
Oxalic Acid SCHEMBL5729545 0.65
Acetic Acid SCHEMBL27759376 0.62 FFAR3 (0.44)
Carbamic Acid SCHEMBL27422028 0.62 ACHE (0.44)
Carbamic Acid SCHEMBL28313671 0.61 ACHE (0.41)
Succinic Acid SCHEMBL2578311 0.59 LMNA (0.50)
Fumaric Acid SCHEMBL8352060 0.59 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2909205-A1 HEPATITIS C VIRUS INHIBITORS Bristol-Myers Squibb Company (US) 2015-08-26 EP disclosed
WO-2014062196-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2014-04-24 WO disclosed
EP-2721053-A1 HEPATITIS C VIRUS INHIBITORS Bristol-Myers Squibb Company (US) 2014-04-23 EP disclosed
EP-2705049-A1 HEPATITIS C VIRUS INHIBITORS Bristol-Myers Squibb Company (US) 2014-03-12 EP disclosed
WO-2012173983-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2012-12-20 WO disclosed
WO-2012151195-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2012-11-08 WO disclosed